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10.1172/jci.insight.99096 93 LiZ.WuZ.YanJ.LiuH.LiuQ.DengY.et al (2019)

On the other hand, since the crystalline form of the pharmaceutical raw material may cause a significant change in physical properties when a crystal transition occurs due to a change over time, there is a possibility that it may cause problems in the production of formulations

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L-CN and GBB concentrations were quantified using D9-l-carnitine and D9--butylbetaine as IS, and both were diluted to 200 ppb by adding 50% methanol in water to the master solution, which was stored at 20 C