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Additionally, the extravasation of immune cells, particularly neutrophils and monocytes, further amplifies the astrocyte activation process through the release of proinflammatory cytokines and chemokines (54)

28 Further, it transformed into water in the presence of catalytic enzymes like glutathione peroxidases (GPx) and peroxiredoxins

Five consecutive sagittal sections of the medial compartment of the tibial plateau per mouse in each group were measured

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Meantime, hepatic and renal function biochemical markers tests exhibited normal ranges of values in the PBS, Gi-F-CAA (8 mg/kg in 100 L PBS), Gi-F-CAA (12 mg/kg in 100 L PBS) and Gi-F-CAA (16 mg/kg in 100 L PBS) treatment groups at 1 day post-injection, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), urea nitrogen (BUN), and creatinine (CRE) levels (Supplementary Fig

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