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Oxidative stress in spermatozoa arises from a combination of endogenous and exogenous sources, with leukocyte-derived ROS, mitochondrial dysfunction, and external environmental factors all playing significant roles in generating ROS and damaging sperm cells

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It may be explained by several factors: DO 2 -VO 2 dependency, the effect of oral water on gut oxygen balance, or body thermogenesis following water ingestion ( 2 that can be diminished by decreasing the amount of enteral nutrition ( b -adrenergic stimulation, as observed with intravenous infusion of epinephrine ( Clinical Implication The present results demonstrated the effectiveness of oral water to improve blood flow and tissue perfusion

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