nac apap overdose mechanism glutathione The Use and Potential Benefits of N-Acetylcysteine in Non-Acetaminophen Acute Liver Failure: An Etiology-Based Review What is the antidote of

What is the antidote of choice for acetaminophen poisoning? N acetylcysteine (NAC) Glutathione Answer in the story Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors The Central Nervous System Modulatory Activities of N Acetylcysteine: A Synthesis of Two Decades of Evidence Acetaminophen (Paracetamol) Toxicity A common and potentially fatal cause of acute liver failure due to toxic accumulation of the metabolite NAPQI when glutathione stores are depleted. Early recognition and timely administration Acetaminophen toxicity EMCrit Project 5 Antidote: NAC (N acetylcysteine) NAC replenishes glutathione, restoring the ability to detoxify NAPQI. It's lifesaving if given early. Example: Hospitals use NAC as the standard treatment for APAP overdose.

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