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Finally, ceramide is produced by a desaturation reaction assisted by dihydroceramide desaturase (DDase) (Quinville et al., 2021

Yousri, N

S., Aguila, M

Genetic polymorphism in cytochrome P450 2D6 (CYP2D6): population distribution of CYP2D6 activity

It provides reduced Glutathione, a powerful antioxidant

This pragmatic approach enables risk-controlled clinical advancement while generating the mechanistic data necessary to guide appropriate use alongside standard antimicrobial or immunomodulatory therapies