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Le TB-500 is a 43-amino-acid peptide that regulates the polymerization of G-actin to F-actin, a process essential for cell migration and wound healing

At higher pH levels, cysteine can form disulfide bonds with other cysteine residues in the same peptide or even in neighboring peptide molecules

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193 Notably, another phase II trial found that although TTM may not improve survival in patients with kidney cancer when used as a monotherapy, it may be more effective when combined with other anti-angiogenic agents