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The kidneys also help maintain a slightly alkaline blood pH (between 7.37 and 7.43) by excreting excess acid or base (Koeppen 2009

This pathway has been explored for its role in reducing visceral fat

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62 This approach could be particularly useful in cases that a large cartilage surface needs to be replaced, and there are signs of joint inflammation

Furthermore, they can be precisely released in response to endogenous stimuli from the microenvironment as well as exogenous stimuli under artificial control