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This study can be a node for developing more mature and controlled studies to evaluate the effect of vitamin B12 as a safe and potentially important moderator of nociplastic pain and psychological illness in FM

Most patients who plateau early are underestimating portion sizes by 2040%, which eliminates the deficit entirely

But if massive doses of individual supplements of B6 and B12 do indeed promote cancer, this is not the first time that mega doses of vitamins have been seen to cause harm

Methanol (LC-MS grade) was purchased from Honeywell (Seelze, Germany)

People with other conditions that cause high ferritin levels may require additional or different treatments

J Pharmacol Exp Ther 324:883893