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Cat#A7250) administered ad libitum in drinking water (900 mg/l

Berberis lycium which is rich in berberine has also been studied for its various cytotoxicity role on cancer cells, the compounds such as oxy berberine and -sitosterol effectively inhibit cell proliferation and hence used in anticancer drug discovery (Xu and Malav, 2001)

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Whilst one phase III trial did not reveal a significant difference in ALSFRS-R score when additional patient inclusion criteria were applied [Oakes et al., 2017

they are used as control medications, and not rescue medications) (Fanta, 2017)

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