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59,72,73 One study in pain-sensitized mice found neutrophils invaded peripheral sensory nerves and increased their pain signaling, whereas neutrophil depletion prevented the mice from developing chronic widespread pain

Demographics: Baseline characteristics reflected a real-world population (median age 64), with 35% of patients presenting with high-risk cytogenetics and 40% with soft-tissue plasmacytomas

When Surgical Delay Is Not Negotiable If the B12 deficiency is severe (particularly if below 100 pmol/L or with neurological symptoms), I do not proceed, regardless of the patients preferences regarding timing

Drains can also be used to ensure proper healing and you may need to manage these according to instructions