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260,264,265 However, one 10-day trial compared 600 mg intravenous SAMe daily to placebo in 34 fibromyalgia patients and found no significant effect from treatment

I used the ILADS web site to get some names near where I live (a much better way is to join some Facebook Lyme groups and ask for recommendations for your area)

Their homocysteine concentrations did not change significantly, and were not different from the other groups

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Recent clinical trials have demonstrated that methylcobalamin can significantly improve neuropathic symptoms and nerve function in patients with DPN

Psychiatric conditions, such as major depressive disorder (MDD) and somatic symptom disorder, were evaluated owing to the patients depression, cognitive disturbances, and persistent musculoskeletal pain [25]