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Moreover, degenerated IVDs contained more nerve fibers and the DRG neurons expressed painrelated neuropeptides that proposedly resulted in plasticity changes in the central nervous system, represented by the progressive astrocyte activation

Mater 19 (19), 581593

Ferrario, MD, FAHA, FISH, FAPS, FACC, is Professor Emeritus (Surgery) and Founder of the Hypertension and Vascular Research Center, Atrium Health Wake Forest School of Medicine

Gq has been well established as an activator of intracellular calcium release from the endoplasmic reticulum (Rhee, 2001

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After all, water is needed for all of the cellular functions necessary for energy production