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Nevertheless, there are certain challenges to this neuron regeneration strategy as well

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DUSP6 protein levels are decreased in murine primary aortic endothelial cells derived from type 1 non-obese diabetic mice and high-glucose-treated human primary aortic endothelial cells [169]

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The incidence rate ratio (IRR) of subsequent cancer in patients with T2DM was 1.73, which was higher than that of individuals without DM, and it increased in both men and women