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Methylmalonic Acid Homocysteine Notes on Clinical Trials of B12 Supplementation Although not addressed in the graphs, younger people who start out deficient tend to have more drastic, initial drops in MMA and homocysteine

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Sartoretto JL, Melo GA, Carvalho MH, Nigro D, Passaglia RT, Scavone C, et al

DOI: 10.3390/nu14091965IF: 5.0 Q1 B2 From NLM

Maximum concentrations are measured 2-4 hrs after the plasmatic peak

Conversely, in WT mice, JNK pathway was activated from 2 to 40 h as evidenced by the enhanced phosphorylation levels of JNK, c-Jun and ATF2 (Figure 6)