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Our understanding of Parkinsons disease (PD) has evolved from the initial focus on motor symptoms to now include non-motor symptoms of the disease (such as mood, fatigue, constipation)

For weight loss specifically, this is not a close comparison

For example, stomach acid may break down certain compounds, and digestive efficiency can vary from person to person

St-Pierre J, Lin J, Krauss S et al (2003) Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells