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Description

Synthesizes glutathione (GSH) Antioxidant that neutralizes hydrogen peroxide (refer to Chapter 2) b

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Deol, Dr

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Cell 29 , 102111 (2008)

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However, NADPH levels in latently infected cells were altered depending on a general depression of nicotinamide metabolism (Figs 2A, 3 and EV4) and on the level of oxidized glutathione, which is generated by HIV1 infection (Shytaj et al , 2020) and reduced by NADPH consumption (Benhar et al , 2016) (Figs 3 and EV4)

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As such, VitC plays a number of important roles in reducing oxidative stress caused by infection, balancing the immune system, and killing microorganisms by generating free radicals

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