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Targeting the tumor microenvironment by intervention in interleukin-1 biology

doi: 10.1016/j.cell.2006.03.043 108 HangauerM

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In this scenario, a deeper understanding of the tissue specificity effects and the molecular mechanisms of PPAR- is mandatory to develop novel and safer therapies

Sua principal funo que recebeu destaque foi por seu envolvimento no transporte de cidos graxos de cadeia longa para dentro da mitocndria, para que possam ser utilizados como fonte de energia, ou seja, para que sejam oxidados