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Furthermore, HRMS-based non-targeted analyses using MS/MS structural elucidation allowed to identify other relatively minor metabolites related to APAP-Cys such as S-(5-acetylamino-2-hydroxyphenyl)mercaptopyruvic acid (SAMP), an APAP metabolite potentially formed by the transamination reaction of APAP-cysteine (see Fig.1), previously observed in mouse ( 29 )

It is the only water-soluble vitamin that is stored in large quantities in the liver

0.136 mol/L, p 139 mmHg and/or diastolic blood pressure 89 mmHg) were excluded, although subjects with normal blood pressure taking anti-hypertensive medication were included

Some patients continue indefinitely under physician supervision with periodic monitoring

Targeting the HDAC6-cilium axis ameliorates the pathological changes associated with retinopathy of prematurity

Liraglutide reduced body weight in both patients with and without diabetes, as well as in children with obesity