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As a classical inhibitor of CBS, aminooxyacetic acid is the most common, but it also inhibits cystathionine gamma-lyase (CSE), which is another enzyme in the transsulfuration pathway [164]

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10.1016/j.ccell.2025.03.031 81 LevineB.KroemerG

For other cancer entities including bladder cancer and oral cavity carcinoma, a downregulation of ODC1 by DNA hypermethylation and subsequently global demethylation has been reported [70,71]