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This allows for more immediate systemic availability and the possibility of localized administration near an injury site

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Vascular endothelial growth factor (VEGF) is the predominant and critical angiogenic protein, binding to its receptor on ECs to promote their proliferation and migration by activating the phosphoinositide 3-kinase-protein kinase B (PI3K-Akt) signaling pathway and the Ras-extracellular signal-regulated kinases1/2 (Ras-Erk1/2) signaling pathway

As we indicated in the CY 2026 OPPS/ASC proposed rule, we believe that adding a standard identifier to the file would advance the comparability of the HPT data with other healthcare data, including health plan transparency data from the Transparency in Coverage (TiC) MRFs