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Taken together, these results demonstrate that C1-27 targets GSTO1 in tumours and shows promising antitumour activity in both cell line xenograft and PDX models of colorectal cancer, without gross systemic toxicities

Currently, EVs have been isolated from animals (Wu and Liu, 2018), plants (Zhuang et al., 2015) and microorganisms (Tao and Guo, 2018)

The ability to easily obtain OTCs makes them attractive as drugs of abuse, even though some of the desired effects, or highs, are less potent and/or shorter in duration than can be achieved by abusing controlled substances

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