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Protective role of hesperetin in sorafenib-induced hepato- and neurotoxicity in mice via modulating apoptotic pathways and mitochondrial reprogramming

PMID: 29155147

Metformin, a well-characterized AMPK activator, has attracted attention for its potential to reprogram macrophage metabolism toward an anti-inflammatory state

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2.4 Study selection, eligibility criteria, and data extraction Reviewers underwent training at each step of the process, and a pilot screening was conducted to ensure consistency in applying the eligibility criteria