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Key GPX1 Variants rs1050450 (Pro198Leu) Leu allele carriers: Reduced GPX1 activity, increased oxidative stress

Salmon, H

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The activation of these mediators such as the receptor interacting protein kinases 1 and 3 (RIPK 1 and 3), result in necrosis while inhibiting apoptosis [122], and RIP3 has been suggested to be a molecular switch between apoptosis and necrosis [123] implicating it as a unique molecular regulator dictating necrotic cell death

Younus H

Autophagy induction by histone deacetylase inhibitors inhibits HIV type 1