oral melanotic macule macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Differential Diagnosis of Pigmented Lesions

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the use of these three drugs in combination for cancer treatment, especially as an adjunct to chemotherapy, is a novel combination providing effects on several of the most important metabolic, intercellular signaling, and intracellular signaling pathways that are dysregulated in pancreatic cancer and other cancers

Subtle shifts in neurotransmitter tone or cellular energy status may influence vascular tone, sensory processing and pain pathways, creating a biologically plausible route by which ALCAR could alter headache susceptibility

[240] have recently shown that selenium can alleviate autistic behaviors in the BTBR mouse model of ASD by inhibiting ferroptosis via activation of the nuclear factor erythroid 2-related factor 2 (Nrf2)/GPX4 signaling pathway

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