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23 78c is a highly specific CD38 inhibitor, which has greater potency than the flavonoids in reversing NAD + decline during aging, thereby improving several age-associated physiological functions, including cardiac function, muscle function and glucose tolerance

8 weeks) in C57BL/6 produces pericentral HSC activation, collagen I/III deposition (Sirius Red staining), and biochemical hepatitis (ALT, AST elevation)

High-dose acetaminophen (300 mg/kg, i.p.) induced ferroptosis in C57BL/6J mice, marked by elevated Fe and malondialdehyde (MDA)