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While a study in chronic insomnia patients has reported that short-term DSIP administration is unlikely to be of major therapeutic benefit, a 16-month study in mice found that long-term DSIP administration increased maximum life span and decreased the rate of tumor growth [22, 23]

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One in vitro study appears to suggest the half-life of DSIP to be around 15 minutes, while animal studies suggest 4-5 minutes