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TANs promote lipid peroxidation driven by the Fenton reaction by forming neutrophil extracellular traps (NETs), releasing DNA-histone complexes and capturing free iron in the microenvironment, thereby increasing local iron concentration by 23 times

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We selected these sequences for further in silico validation of folding propensity by an orthogonal approach relying on Rosetta cyclic peptide structure prediction methods 18,20 (see Methods, Energy landscape calculation and analysis)

Antonoff MB , Verrier ED, Yang S, Lin J, DeArmond DT, Allen MS, Varghese TK, Sengewald D, Vaporciyan AA

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