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For example, researchers have found that elevated levels of lead are associated with a higher risk of ALS (Fang 2010)

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Clin Immunol Immunopathol 80: 283289 Hurwitz BE, Klimas NG, Llabre MM, Maher KJ, Skyler JS, Bilsker MS, McPhersonBaker S, Lawrence PJ, Laperriere AR, Greeson JM et al (2004) HIV, metabolic syndrome X, inflammation, oxidative stress, and coronary heart disease risk : role of protease inhibitor exposure

Aliquots were treated with the indicated compounds (100 M) or DMSO for 30 min at room temperature

NAD+ also helps to maintain a healthy metabolism