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JNJ-10181457, a selective non-imidazole histamine H(3) receptor antagonist, normalizes acetylcholine neurotransmission and has efficacy in translational rat models of cognition

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Similar to blocking S protein-ACE2 binding, inhibiting cleavage of the S protein has been effective at restricting virus entry in vitro

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PLoS ONE 2014 , 9 , e107895