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TMEM19 was knocked down in iPS cell-MPCs using siTMEM19 or scrambled short interfering RNA (Scr siRNA) as control, then cells were treated with either empty nanoparticles (C 18 -pSi) or erucamide (Eru-C 18 -pSi)

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215 Upon internalization by tumor cells, HZCO releases Cu and Zn in response to the tumor microenvironment, triggering mitochondrial dysfunction, ER stress, and the accumulation of ROS and cytosolic dsDNA

Methods: We generated HLOs from 74 surgical specimens (28 I/I, 32 I/M and 14 M/M for PNPLA3 p.I148M)

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9.4 Jasmonic acid The ROS wave orchestrates a wide range of physiological, molecular, and metabolic responses across different plant organs and plays a pivotal role in systemic acquired acclimation (SAA) under stress conditions