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doi: 10.1017/S0007114520000380 154

p-IKK, Phosphorylated IB kinase alpha

Oxidative stress can render tumor cells insensitive to anti-proliferative signals, apoptosis, and anchorage-independent growth, which alters tumor cell invasion and migration through epigenetic and metabolic mechanisms, further contributing to colorectal cancer development and progression (Ziczuk et al., 2020)