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Preliminary research suggests that these mechanisms may be similar to those observed with exogenous hGH therapy, including the activation of the adrenergic receptors and increased lipolysis in adipocytes [5]

These include diet, medical conditions, and some medicines

Avoid alcohol and caffeine as they can increase inflammation

In cases where the skin barrier is weak and it is highly inflamed, the hands and face are more prone to environmental damage

In some cases, a bone marrow biopsy may be necessary

intramuscular route: count injections given Visit 4 (week 52) Anamnesis: record lifestyle habits and use of alcohol Symptoms: record paresthesia, asthenia, loss or reduction of appetite, sadness or change in level of happiness, and concomitant pharmacological treatment Physical examination: for Hunters glositis, positional and vibrational sensitivity Record concomitant treatment Questionnaires: EuroQoL-5D, satisfaction and preferences Assessment of haemogram and serum vitamin B12 concentration Assessment of adverse effects Assess adherence to treatment: oral route count number of vials used