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Additionally, in the context of lowered ATP production, which is a hallmark of mitochondrial diseases, it is important to note that NAC, essentially only being a form of cysteine, will require 2 ATP molecules to be converted to glutathione

To further confirm these results, we repeated the YLG hydrolysis assays using ShD14 and OsD14 and obtained the same results as previously published 28 (Supplementary Fig