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1) This paper first reviewed the biological functions of mitochondria, including mitochondria-mediated ROS, mitochondria-mediated apoptosis, mitochondrial dynamics, mitochondrial autophagy and mitochondria-mediated Ca 2+ homeostasis

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Methods Construction of hexahistidine-tagged recombinant human GPx3 (rhGPx3) mutant expression vector A GPx3 mutant gene without signal peptide sequence (nucleic acids 160) was designed on the basis of the cDNA sequence of human GPx3 (GenBank accession No

Francis AM, Sepesi B, Correa AM, Blum MA, Erasmus JJ, Lee JH, Maru DM, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Welsh JW, Swisher SG , Hofstetter WL

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Exploring the epileptogenic mechanism of the familial focal epilepsy-related gene NPRL3 in Drosophila melanogaster The mTORC1 pathway plays a pivotal role in modulating responses to environmental stimuli, including nutrients and growth factors