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Comparison of continuous and intermittent anorectic therapy in obesity

Having digestive disorders like Chrons disease and celiac disease and drinking too much alcohol might impair vitamin B12 absorption leading to its deficiency

For a fixed value of dose per day, the narrower the dosing interval with divided dosing the narrower the gap in blood levels between peak and trough

Treating hypocobalaminemia (B12 deficiency)

(Lee et al., 2005) documented significantly elevated NNMT expression in abdominal subcutaneous adipocytes of obese Pima Indians relative to non-obese counterparts