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The disease frequently produces goitrous myxedema in young women, and we have occasionally observed a goitrous and hypothyroid patient who went on to develop thyroid atrophy.Occasionally, patients with Hashimoto thyroiditis have persistent pain which is unresponsive to nonsteroidal anti-inflammatory drugs, replacement with thyroid hormone, and recurs after therapy with steroids

The Nuclear receptor coactivator 4 (NCOA4) is an important molecule that mediates ferroptosis, and silencing NCOA4 decreases the level of liable iron pools and inhibits ferroptosis [14, 27]