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In the cytosol, acetyl-CoA can also be derived from acetoacetyl-CoA, which can originate from acetoacetate through the sequential actions of acetoacetyl-CoA synthetase (in an ATP-dependent manner) and subsequently the cytosolic isoform of acetoacetyl-CoA thiolase (Fig

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IAV infection activates NF-B binding and induces the expression of antioxidant genes, including manganese SOD and indoleamine 2,3-dioxygenase, in human airway epithelial cells 78,79

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