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The underlying pathophysiology of facial synkinesis is likely multifactorial, although the predominant mechanism appears to be aberrant regeneration of facial nerve fibres to the facial muscle groups following facial nerve injury [4]

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Protein expression We used the Bac-to-Bac baculovirus system (Thermo Fisher) in Spodoptera frugiperda ( sf9 ) cells for expression

3.3.1 Pre-synaptic dysfunction via A In pathological conditions, A aggregates in synapses resulting from abnormal build-up of the BACE1 which is a crucial neuronal - secretase involved in A production