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Vitamin B12 is a water-soluble vitamin which has important roles in nervous system, liver function and is involved in energy metabolism and red blood cell formation

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However, a single daily dose is also very common, particularly for convenience in long-term studies

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Production of serotonin Figure 4 , is critically dependent upon the action of the enzyme Tryptophan-5-Hydroxylase (TPH), followed by the subsequent reaction of the PLP dependent enzyme, Hydroxy-Tryptophan Decarboxylase (HTD)