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For nucleic acids, typically from about 30 to about lOOg of nucleic acid is injected into a 70 kg patient, more typically, about 50 to 150g of nucleic acid is injected, followed by boosting treatments as appropriate

Notably, the Gprc5a -ko mouse lung cancer model exhibits two significant characteristics: the spontaneous development of lung tumors and a persistent state of inflammation

Taken together, these results suggest that CRIP1 promotes cancer stemlike properties in HCC

doi: 10.15252/embj.201696151 68 YangLVennetiSNagrathD

K.TripathiA.RustagiS.et al

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