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In a meta-analysis that pooled findings from six randomized controlled trials with a total of 301 participants, vitamin D was found to reduce migraine frequency, number of days affected by migraine, and migraine-related disability scores (Hu 2021)

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Factors affecting individual response Response to AHK-Cu varies substantially between individuals

FIGURE 2 Although TCA cycle is at the nexus of both catabolic and anabolic metabolism involving different key fuel molecules and metabolites, it was recently reported that alteration of amino acid metabolism is the main consequence of TCA cycle disruption (Ryan et al., 2021)

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