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Recent research explored the prognostic value of increased serum homocysteine concentration in PE, especially during the first trimester of pregnancy, suggesting homocysteine as a predictor of PE [31]

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Altogether, these interrelated mechanisms create a pathological environment and further progressive neuronal damage, forming the biological basis of neurodegenerative diseases

Zheng Su, [email protected] These authors have contributed equally to this work This article was submitted to Biofilms, a section of the journal Frontiers in Cellular and Infection Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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This procedure helped in 5 clinical trials on over 600 children and prevented the need for surgery in most cases