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More deeply, the ability of zinc to inhibit the production of NO through inducible (iNOS) and constitutive NOS (cNOS) is responsible for the reported anti-inflammatory effect of zinc (219)

Loss of CLTRN function produces a neuropsychiatric disorder and a biochemical phenotype that mimics Hartnup disease

P2X7R-mediated autophagic impairment contributes to central sensitization in a chronic migraine model with recurrent nitroglycerin stimulation in mice

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5,6 Globally, GI disorders such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), gastroesophageal reflux disease (GERD), constipation, dyspepsia, and peptic ulcers represent a major health burden