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Recasens-Alvarez, C., Heap, G

Mao, W., Kim, H

Therefore, focusing on mechanisms contributing to cognitive decline in aging and identifying solutions to improve or reverse ACD will (a) have benefits for improving cognitive health in older adults, and (b) could identify potentially viable mechanistic clues for understanding and combating AD and dementia, especially because both aging and AD share several common associations

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REW-IgG subclasses show favorable FcRn engagement but distinct effector functions As the REW substitutions are conserved among the four human IgG subclasses, we made REW engineered anti-NIP versions, in addition to a recombinant form of the IgG1 Fc fusion molecule etanercept (Fig