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Interdisciplinary approaches help address complex questions and provide a more comprehensive view of their roles in pathology

141,142 ERS-induced apoptosis in cells is largely dependent on increasing CHOP and decreasing BCL-2, while activation of IKK and JNK1 by IRE1 binding with TRAF2 also promotes mitochondria-mediated apoptosis in cells 37,58,59 (Fig

Plasma, the liquid portion of blood, consists mostly of water and proteins, facilitating the movement of blood cells and platelets throughout the body