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Description

HO-1 expression was significantly reduced during dendritic cell maturation in vitro, which corresponds to the absence of HO-1 expression by mature dendritic cells in human tissues

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There is substantial evidence that the STAT3-dependent signaling induces the polarization of macrophages toward the immunosuppressive M2 phenotype [112]

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Interestingly, in renal clear cell carcinoma, IDO expressed by neovascularization endothelial cells is an inhibitory factor in tumor growth because it limits the flow of tryptophan from the blood to the tumor or produces tumor toxic substances (Riesenberg et al., 2007)

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10.1146/annurev-immunol-101320-011235 165 OakesS

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Polyethylene microbeads are more critically toxic to the eyes and reproduction than the kidneys or growth in medaka, Oryzias latipes

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