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Final conclusion: IV infusion: dilute in 5% dextrose stable and chloride-free

Centenarians have plasma MOTS-c levels resembling those of people decades younger, suggesting preserved mitochondrial signaling is a feature of exceptional aging

Buffer composition, pH, and ionic strength may affect peptide stability

A preservative-free and a lower strength ophthalmic solution were FDA-approved in November 1997 and May 2003, respectively

Discussion Diagnostic approach and differential diagnoses The patient presented with signs and symptoms indicative of TMA: fatigue, delirium, acute kidney injury, elevated LDH, anemia, schistocytes on peripheral smear, and hyperbilirubinemia