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The protective effect of alpha-lipoic Acid in lipopolysaccharide-induced acute lung injury is mediated by heme oxygenase-1

It is likely that neurons maintain functional autophagy and/or buffer the accumulation of these proteins for many years by using other proteostasis mechanisms, including the ubiquitinproteasome pathway and CMA

Uribe-Lewis S, Uribe J, Bourke V, Deering C, Higgins D, Mehta S, et al

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The most common causes of degradation include: Heat exposure Moisture contamination UV light Oxidation Freeze-thaw cycles Bacterial contamination after reconstitution Improper storage may affect peptide stability and reduce consistency in laboratory analysis

2010 May;77(9):834