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Injectable healing protocol: 23 mg daily (upper end of range), systemic injection - not into the wound itself - daily until the wound resolves, plus 12 weeks maintenance Topical healing protocol: 2 %4 % in a wound-appropriate vehicle applied 23 times daily to wound margins (never into an open, actively bleeding wound) under clinician supervision Stacking: GHK-Cu pairs exceptionally well with BPC-157 and TB-500 - the so-called GLOW stack - for complex healing cases

4 Pharmacokinetic properties A full understanding of its behavior in biological systems, essential for further caudatin development as a clinical agent, can only be achieved since the pharmacokinetic (PK) profile determines absorption, distribution, metabolism, and elimination (ADME), and parameters that control both safety and efficacy ( Quantitative characterization of the caudatin PK profile has been primarily derived from studies in rats, and particularly those that have successfully quantified using sensitive UPLC-MS/MS technology (Zhu et al., 2015) with a linear range established from 2.5 to 300 ng/mL in rat plasma

Initial protocols often use weekly injections for 48 weeks, then transition to biweekly or monthly maintenance

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