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Genetic predisposition for immune system, hormone, and metabolic dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome: A pilot study

2001 Dec;142(12):5182-9

Supplemental zinc lowers measures of iron status in young women with low iron reserves

This makes it very reliable, but it also has some properties that make it quite annoying to use: it is quite unstable , especially when dissolved in water it oxidizes quickly and has a short shelf life